Children's Hospital Oakland, Hematology/Oncology

Hematology/Oncology Division at Children's Hospital & Research Center Oakland

Recent Faculty Publications (2011 - 2013)

Books:

  • Hastings CA, Torkildson JC, Agrawal AK. Handbook of Pediatric Hematology and Oncology: Children's Hospital and Research Center Oakland. Second ed. West Sussex, United Kingdom: John Wiley & Sons, Ltd.; 2012. http://www.amazon.com/Handbook-Pediatric-Hematology-Oncology-Childrens/dp/0470670886

  • Musallam KM, Rivella S, Vichinsky E, Rachmilewitz EA. Non-Transfusion-Dependent Thalassemias. Thalassaemia International Federation; 2013 (in press).

  • Vichinsky E, Levine L, Bhatia S, Bojanowski J, Coates T, Foote D, Fung E, Harmatz P, Jeng M, Knudsen J, Lal A, Pakbaz Z, Schroepfer C, Singer ST, Sweeters N, Walters M, Wood J. Standards of Care Guidelines for Thalassemia. Oakland, California: Children's Hospital & Research Center Oakland; 2012. http://hemonc.cho.org/thalassemia/documents/SOCGuidelines2012.pdf

Edited Books:

  • Feusner J, Hastings C, eds. Supportive Care in Pediatric Oncology, 3rd ed.: Springer; 2013 (in press).

  • Vichinsky EP, ed. Novel Therapies in Hemoglobinopathies: Saunders; 2013 (in press).

Book Chapters:

Journal Articles:

  • Adam SS, Hoppe C. Potential role for statins in sickle cell disease. Pediatr Blood Cancer 2013;60 4:60;4 p.550-7. http://www.ncbi.nlm.nih.gov/pubmed/23281161

  • Afshar M, Golden C. Report of Neuroblastoma in a Set of Monozygotic Monochorionic Twins. Pediatr Hematol Oncol 2013. http://www.ncbi.nlm.nih.gov/pubmed/23373760

  • Agrawal AK, Chang PP, Feusner J. Twice weekly Pneumocystis jiroveci pneumonia prophylaxis with trimethoprim-sulfamethoxazole in pediatric patients with acute lymphoblastic leukemia. J Pediatr Hematol Oncol 2011;33 1:e1-4. http://www.ncbi.nlm.nih.gov/pubmed/21102354

  • Agrawal AK, Golden C, Matsunaga A. Acquired von Willebrand disease in an osteosarcoma patient. J Pediatr Hematol Oncol 2011;33 8:622-3. http://www.ncbi.nlm.nih.gov/pubmed/22042279

  • Agrawal AK, Guo H, Golden C. Siblings presenting with progressive congenital aleukemic leukemia cutis. Pediatr Blood Cancer 2011;57 2:338-40. http://www.ncbi.nlm.nih.gov/pubmed/21425444

  • Agrawal AK, Haddad FG, Matsunaga A. Acute nonimmune hemolytic anemia without fulminant hepatitis in Wilson disease. J Pediatr Hematol Oncol 2011;33 4:e163-5. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21516016

  • Agrawal AK, Hsu E, Quirolo K, Neumayr LD, Flori HR. Red blood cell transfusion in pediatric patients with severe chronic anemia: how slow is necessary? Pediatr Blood Cancer 2012;58 3:466-8. http://www.ncbi.nlm.nih.gov/pubmed/21793178

  • Agrawal AK, Kammen BF, Guo H, Donthineni R. An unusual presentation of subcutaneous granuloma annulare in association with juvenile-onset diabetes: case report and literature review. Pediatr Dermatol 2012;29 2:202-5. http://www.ncbi.nlm.nih.gov/pubmed/22085091

  • Agrawal AK, Saini N, Gildengorin G, Feusner JH. Is routine computed tomographic scanning justified in the first week of persistent febrile neutropenia in children with malignancies? Pediatr Blood Cancer 2011;57 4:620-4. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21265012

  • Aguilar A, Saba JD. Truth and consequences of sphingosine-1-phosphate lyase. Adv Biol Regul 2012;52 1:17-30. http://www.ncbi.nlm.nih.gov/pubmed/21946005

  • Amstrong D, Neumayr L, Gold JI, Weiner MW, Rule RR, LeBeau P, Kesler K, McMahon L, Orringer EP, Harrington T, DeCastro LM, Kalinyak K, Kutlar A, Rutherford CJ, Johnson C, Bessman JD, Hussein A, Vichinsky EP. Biologic predictors of memory, attention, and executive function in neurologically asymptomatic adults with sickle cell anemia. 2013 (submitted).

  • Bae HT, Baldwin CT, Sebastiani P, Telen MJ, Ashley-Koch A, Garrett M, Hooper WC, Bean CJ, Debaun MR, Arking DE, Bhatnagar P, Casella JF, Keefer JR, Barron-Casella E, Gordeuk V, Kato GJ, Minniti C, Taylor J, Campbell A, Luchtman-Jones L, Hoppe C, Gladwin MT, Zhang Y, Steinberg MH. Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans. Blood 2012;120 9:1961-2. http://www.ncbi.nlm.nih.gov/pubmed/22936743

  • Ballas SK, Kesen MR, Goldberg MF, Lutty GA, Dampier C, Osunkwo I, Wang WC, Hoppe C, Hagar W, Darbari DS, Malik P. Beyond the definitions of the phenotypic complications of sickle cell disease: an update on management. ScientificWorldJournal 2012;2012:949535. http://www.ncbi.nlm.nih.gov/pubmed/22924029

  • Ballas SK, Kesen MR, Goldberg MF, Lutty GA, Dampier C, Osunkwo I, Wang WC, Hoppe C, Hagar W, Darbari DS, Malik P. Erratum to "Beyond the Definitions of the Phenotypic Complications of Sickle Cell Disease: An Update on Management". ScientificWorldJournal 2013;2013:861251. http://www.ncbi.nlm.nih.gov/pubmed/23483854

  • Benson RC, Hardy KA, Morris CR. Arginase and arginine dysregulation in asthma. J Allergy (Cairo) 2011;2011:736319. http://www.ncbi.nlm.nih.gov/pubmed/21747870

  • Bloch EM, Herwaldt BL, Leiby DA, Shaieb A, Herron RM, Chervenak M, Reed W, Hunter R, Ryals R, Hagar W, Xayavong MV, Slemenda SB, Pieniazek NJ, Wilkins PP, Kjemtrup AM. The third described case of transfusion-transmitted Babesia duncani. Transfusion 2012;52 7:1517-22. http://www.ncbi.nlm.nih.gov/pubmed/22168221

  • Chen Q, Fabry ME, Rybicki AC, Suzuka SM, Balazs TC, Etzion Z, de Jong K, Akoto EK, Canterino JE, Kaul DK, Kuypers FA, Lefer D, Bouhassira EE, Hirsch RE. A transgenic mouse model expressing exclusively human hemoglobin E: indications of a mild oxidative stress. Blood Cells Mol Dis 2012;48 2:91-101. http://www.ncbi.nlm.nih.gov/pubmed/22260787

  • Chokkalingam AP, Metayer C, Scelo G, Chang JS, Schiffman J, Urayama KY, Ma X, Hansen HM, Feusner JH, Barcellos LF, Wiencke JK, Wiemels JL, Buffler PA. Fetal growth and body size genes and risk of childhood acute lymphoblastic leukemia. Cancer Causes Control 2012;23 9:1577-85. http://www.ncbi.nlm.nih.gov/pubmed/22878902

  • Chu J, Guo H, Raphael R, Torkildson J, Vichinsky E, Garrett C, Hastings C. Disseminated juvenile xanthogranuloma culminating in bone marrow necrosis and death. 2013 (submitted).

  • Cooper TM, Franklin J, Gerbing RB, Alonzo TA, Hurwitz C, Raimondi SC, Hirsch B, Smith FO, Mathew P, Arceci RJ, Feusner J, Iannone R, Lavey RS, Meshinchi S, Gamis A. AAML03P1, a pilot study of the safety of gemtuzumab ozogamicin in combination with chemotherapy for newly diagnosed childhood acute myeloid leukemia: a report from the Children's Oncology Group. Cancer 2012;118 3:761-9. http://www.ncbi.nlm.nih.gov/pubmed/21766293

  • Cui J, Azimi M, Adekile AD, Al Awadhi H, Hoppe CC. Detection of anti-Lepore Hb P-Nilotic by multiplex ligation-dependent probe amplification. Hemoglobin 2012;36 3:276-82. http://www.ncbi.nlm.nih.gov/pubmed/22384950

  • Cui J, Baysdorfer C, Azimi M, Vichinsky EP, Hoppe CC. Identification of three novel Hb F variants: Hb F-Hayward [Ggamma1(NA1)Gly-->Asp, GGT>GAT], Hb F-Chori-I [AgammaT16(A13)Gly-->Asp, GGC>GAC] and Hb F-Chori-II [AgammaI29(B11)Gly-->Glu, GGA>GAA]. Hemoglobin 2012;36 3:305-9. http://www.ncbi.nlm.nih.gov/pubmed/22384921

  • DeBaun MR, Armstrong FD, McKinstry RC, Ware RE, Vichinsky E, Kirkham FJ. Silent cerebral infarcts: a review on a prevalent and progressive cause of neurologic injury in sickle cell anemia. Blood 2012;119 20:4587-96. http://www.ncbi.nlm.nih.gov/pubmed/22354000

  • Delgado EM, Cho CS, Gildengorin G, Leibovich SA, Morris CR. SPeAK Asthma: A study of pediatric adherence and knowledge of asthma. Acad Emerg Med 2013 (under review).

  • Doh I, Lee WC, Cho YH, Pisano AP, Kuypers FA. Deformation measurement of individual cells in large populations using a single-cell microchamber array chip. Appl Phys Lett 2012;100 17:173702-1737023. http://www.ncbi.nlm.nih.gov/pubmed/22586355

  • Douer D, Zickl LN, Schiffer CA, Appelbaum FR, Feusner JH, Shepherd L, Willman CL, Bloomfield CD, Paietta E, Gallagher RE, Park JH, Rowe JM, Wiernik PH, Tallman MS. All-trans retinoic acid and late relapses in acute promyelocytic leukemia: Very long-term follow-up of the North American Intergroup Study I0129. Leuk Res 2013. http://www.ncbi.nlm.nih.gov/pubmed/23528262

  • Dror DK, King JC, Durand DJ, Fung EB, Allen LH. Feto-maternal vitamin D status and infant whole-body bone mineral content in the first weeks of life. Eur J Clin Nutr 2012;66 9:1016-9. http://www.ncbi.nlm.nih.gov/pubmed/22781021

  • Dror DK, King JC, Fung EB, Van Loan MD, Gertz ER, Allen LH. Evidence of associations between feto-maternal vitamin D status, cord parathyroid hormone and bone-specific alkaline phosphatase, and newborn whole body bone mineral content. Nutrients 2012;4 2:68-77. http://www.ncbi.nlm.nih.gov/pubmed/22413062

  • Flanagan JM, Sheehan V, Linder H, Howard TA, Wang YD, Hoppe CC, Aygun B, Adams RJ, Neale GA, Ware RE. Genetic mapping and exome sequencing identify two mutations associated with stroke protection in pediatric patients with sickle cell anemia. Blood 2013. http://www.ncbi.nlm.nih.gov/pubmed/23422753

  • Fung EB, Aguilar C, Micaily I, Haines D, Lal A. Treatment of vitamin D deficiency in transfusion-dependent thalassemia. Am J Hematol 2011;86 10:871-3. http://www.ncbi.nlm.nih.gov/pubmed/21818763

  • Fung EB, Gariepy CA, Sawyer AJ, Higa A, Vichinsky EP. The effect of whole body vibration therapy on bone density in patients with thalassemia: a pilot study. Am J Hematol 2012;87 10:E76-9. http://www.ncbi.nlm.nih.gov/pubmed/22886910

  • Fung EB, Kwiatkowski J, Huang J, Gildengoren G, King JC, Vichinsky EP. Zinc Supplementation Improves Bone Density in Patients with Thalassemia: A double blind, randomized placebo controlled trial. Am J Clin Nutr 2013 (accepted).

  • Fung EB, Vichinsky EP, Kwiatkowski JL, Huang J, Bachrach LK, Sawyer AJ, Zemel BS. Characterization of low bone mass in young patients with thalassemia by DXA, pQCT and markers of bone turnover. Bone 2011;48 6:1305-12. http://www.ncbi.nlm.nih.gov/pubmed/21443975

  • Fung EB, Xu Y, Trachtenberg F, Odame I, Kwiatkowski JL, Neufeld EJ, Thompson AA, Boudreaux J, Quinn CT, Vichinsky EP, Thalassemia Clinical Research N. Inadequate dietary intake in patients with thalassemia. J Acad Nutr Diet 2012;112 7:980-90. http://www.ncbi.nlm.nih.gov/pubmed/22551675

  • Gallagher RE, Moser BK, Racevskis J, Poire X, Bloomfield CD, Carroll AJ, Ketterling RP, Roulston D, Schachter-Tokarz E, Zhou DC, Chen IM, Harvey R, Koval G, Sher DA, Feusner JH, Tallman MS, Larson RA, Powell BL, Appelbaum FR, Paietta E, Willman CL, Stock W. Treatment-influenced associations of PML-RARalpha mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia. Blood 2012;120 10:2098-108. http://www.ncbi.nlm.nih.gov/pubmed/22734072

  • Garcia JR, Pollard J, Thomson B. Minimal Residual Disease in Acute Leukemias: review of literature and introduction of “bridging therapy” prior to hematopoietic cell transplantation. 2013 (submitted).

  • Gladwin MT, Barst R, Gibbs JS, Hildesheim M, Sachdev V, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Zang Y, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Taylor JGt, Goldsmith JC, Gordeuk V, Kato GJ, Machado R, Walk_Phasst_Investigators. Risk factors for death in 632 patients with sickle cell anemia in the United States and United Kingdom. Blood 2013 (under review).

  • Gladwin MT, Kato GJ, Weiner D, Onyekwere OC, Dampier C, Hsu L, Hagar RW, Howard T, Nuss R, Okam MM, Tremonti CK, Berman B, Villella A, Krishnamurti L, Lanzkron S, Castro O, Gordeuk VR, Coles WA, Peters-Lawrence M, Nichols J, Hall MK, Hildesheim M, Blackwelder WC, Baldassarre J, Casella JF, Investigators D. Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial. JAMA 2011;305 9:893-902. http://www.ncbi.nlm.nih.gov/pubmed/21364138

  • Gold JI, Treadwell M, Weissman L, Vichinsky E. The mediating effects of family functioning on psychosocial outcomes in healthy siblings of children with sickle cell disease. Pediatr Blood Cancer 2011;57 6:1055-61. http://www.ncbi.nlm.nih.gov/pubmed/21360652

  • Gomez E, Morris CR. Asthma management in sickle cell disease. European Respiratory Disease 2013 (in press).

  • Green NS, Ender KL, Pashankar F, Driscoll C, Giardina PJ, Mullen CA, Clark LN, Manwani D, Crotty J, Kisselev S, Neville KA, Hoppe C, Barral S. Candidate sequence variants and fetal hemoglobin in children with sickle cell disease treated with hydroxyurea. PLoS One 2013;8 2:e55709. http://www.ncbi.nlm.nih.gov/pubmed/23409025

  • Grigoriev Y, Lange J, Peterson SM, Takashima JR, Ritchey ML, Ko D, Feusner JH, Shamberger RC, Green DM, Breslow NE. Treatments and outcomes for end-stage renal disease following Wilms tumor. Pediatr Nephrol 2012;27 8:1325-33. http://www.ncbi.nlm.nih.gov/pubmed/22430485

  • Gyang E, Yeom K, Hoppe C, Partap S, Jeng M. Effect of chronic red cell transfusion therapy on vasculopathies and silent infarcts in patients with sickle cell disease. Am J Hematol 2011;86 1:104-6. http://www.ncbi.nlm.nih.gov/pubmed/21117059

  • Haines D, Martin M, Carson S, Oliveros O, Green S, Coates T, Eile J, Schilling L, Dinu B, Mendoza T, Gerstenberger E, Trachtenberg F, Vichinsky E, Thalassemia Clinical Research N. Pain in thalassaemia: the effects of age on pain frequency and severity. Br J Haematol 2013;160 5:680-7. http://www.ncbi.nlm.nih.gov/pubmed/23278768

  • Hoppe C, Kuypers F, Larkin S, Hagar W, Vichinsky E, Styles L. A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction. Br J Haematol 2011;153 5:655-63. http://www.ncbi.nlm.nih.gov/pubmed/21477202

  • Hoppe CC. Newborn screening for hemoglobin disorders. Hemoglobin 2011;35 5-6:556-64. http://www.ncbi.nlm.nih.gov/pubmed/21910601

  • Hoppe CC. Novel therapies targeting the endothelium in sickle cell disease. Hemoglobin 2011;35 5-6:530-46. http://www.ncbi.nlm.nih.gov/pubmed/21910600

  • Hue-Roye K, Hipsky CH, Velliquette RW, Fuchisawa A, Lomas-Francis C, Hoppe C, Reid ME. A novel RHCE*ce 48C, 733G allele with Nucleotide 941C in Exon 7 encodes an altered red blood cell e antigen. Transfusion 2011;51 1:32-5. http://www.ncbi.nlm.nih.gov/pubmed/20576012

  • Hung K, Killilea D, Firnkes S, Ory D, Volitakis I, Hastings C, Bush A. NPC1 modulates metal homeostasis: a metallomic analysis. Metallomics (submitted, May 2011) 2011.

  • Jacobs JE. Invasive aspergillus Infections in Hospitalized Pediatric Oncology Patients. 2013 (submitted).

  • Jacobs JE, Quirolo K, Vichinsky E. Novel influenza A (H1N1) viral infection in pediatric patients with sickle-cell disease. Pediatr Blood Cancer 2011;56 1:95-8. http://www.ncbi.nlm.nih.gov/pubmed/20973097

  • Jordan LB, Smith-Whitley K, Treadwell MJ, Telfair J, Grant AM, Ohene-Frempong K. Screening U.S. college athletes for their sickle cell disease carrier status. Am J Prev Med 2011;41 6 Suppl 4:S406-12. http://www.ncbi.nlm.nih.gov/pubmed/22099365

  • Kamani NR, Walters MC, Carter S, Aquino V, Brochstein JA, Chaudhury S, Eapen M, Freed BM, Grimley M, Levine JE, Logan B, Moore T, Panepinto J, Parikh S, Pulsipher MA, Sande J, Schultz KR, Spellman S, Shenoy S. Unrelated donor cord blood transplantation for children with severe sickle cell disease: results of one cohort from the phase II study from the Blood and Marrow Transplant Clinical Trials Network (BMT CTN). Biol Blood Marrow Transplant 2012;18 8:1265-72. http://www.ncbi.nlm.nih.gov/pubmed/22343376

  • Kanathezhath B, Feusner J. Evaluation of: [Khorana AA et al. Can literature enhance oncology training? A pilot humanities curriculum. J Clin Oncol. 2011 Feb 1; 29(4):468-71; doi: 10.1200/JCO.2010.33.3617]. 11 Mar 2011 http://F1000.com/8865959

  • Kanathezhath B, Mizokami M, Stanislaus S, Hounshell C, Neumayr L, Guo H, Hearst JE, Walters MC, Kuypers FA. Improved engraftment with minimal graft-versus-host disease after major histocompatibility complex-mismatched cord blood transplantation with photochemically treated donor lymphocytes. Exp Biol Med (Maywood) 2011;236 4:492-504. http://www.ncbi.nlm.nih.gov/pubmed/21454375

  • Kanathezhath B, Shenvi S, Guo H, Kuypers FA, Walters MC, Ames B, Suh J. Severity of Graft versus Host Disease in murine experimental transplantation is predicted by Host Nrf2-glutathione redox dysregulation. 2013 (submitted).

  • Kanathezhath B, Shenvi S, Guo H, Walters MC, Ames B, Suh J. Glutathione redox depletion precedes and regulates pro-inflammatory cytokine elevation in experimental graft versus host disease. 2013 (submitted).

  • Kanathezhath B, Shenvi S, Johl A, Manmohan R, Bhandhal MK, Oh D, Zhou A, Kuypers FA, Walters MC, Ames BN, Suh J. Systemic and Hepatic Thiol Redox Dysregulation in Graft Versus Host Disease. Biology of blood and marrow transplantation: Journal of the American Society for Blood and Marrow Transplantation 2012;18 2:S359-S60. http://linkinghub.elsevier.com/retrieve/pii/S1083879111009748?showall=true

  • Kanathezhath B, Suh J, Guo H, Ho J, Siu K, Gieng J, Bhandal M, Ali A, Kuypers F, Walters AM, Ames B. Defective Host Nrf2 function contributes to heightened oxidative stress and correlates with disease severity in experimental graft versus host disease. Biology of Blood and Marrow Transplantation 2013 (under review).

  • Klings E, Machado R, Barst R, Morris CR, Mubarak K, Gordeuk V, Kato GJ, Ataga K, Gibbs JS, Castro O, Berman-Rosenzweig E, Sood N, Hsu L, Wilson KC, Telen M, DeCastro LM, Krishnamurti L, Steinberg MH, Badesch DB, Gladwin MT. Consensus-Based Guidelines for the Diagnosis and Treatment of Pulmonary Hypertension of Sickle Cell Disease. Am J Respir Crit Care Med 2013 (under review).

  • Kutlar A, Ataga K, Reid M, Vichinsky EP, Neumayr L, Blair-Britt L, Labotka R, Glass J, Keefer JR, Wargin WA, Berenson R, Perrine SP. A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease. Am J Hematol 2012;87 11:1017-21. http://www.ncbi.nlm.nih.gov/pubmed/22887019

  • Kutlar A, Ataga KI, McMahon L, Howard J, Galacteros F, Hagar W, Vichinsky E, Cheung AT, Matsui N, Embury SH. A potent oral P-selectin blocking agent improves microcirculatory blood flow and a marker of endothelial cell injury in patients with sickle cell disease. Am J Hematol 2012;87 5:536-9. http://www.ncbi.nlm.nih.gov/pubmed/22488107

  • Kutny MA, Moser BK, Laumann K, Feusner JH, Gamis A, Gregory J, Larson RA, Powell BL, Stock W, Willman CL, Woods WG, Meshinchi S. FLT3 mutation status is a predictor of early death in pediatric acute promyelocytic leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer 2012;59 4:662-7. http://www.ncbi.nlm.nih.gov/pubmed/22378655

  • Kuypers FA, Marsh AM. Research in athletes with sickle cell trait: just do it. J Appl Physiol 2012;112 9:1433. http://www.ncbi.nlm.nih.gov/pubmed/22362400

  • Kwiatkowski J, Kim HY, Thompson A, Quinn C, Mueller B, Odame I, Giardina P, Vichinsky E, Boudreaux JM, Porter J, Coates T, Olivieri N, Neufeld E. Chelation Choices and Iron Burden Among Patients with Thalassemia in the 21st Century. 2013 (submitted).

  • Kwiatkowski JL, Kim HY, Thompson AA, Quinn CT, Mueller BU, Odame I, Giardina PJ, Vichinsky EP, Boudreaux JM, Cohen AR, Porter JB, Coates T, Olivieri NF, Neufeld EJ, Thalassemia Clinical Research N. Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort. Blood 2012;119 12:2746-53. http://www.ncbi.nlm.nih.gov/pubmed/22279056

  • Kwiatkowski JL, Yim E, Miller S, Adams RJ, Investigators SS. Effect of transfusion therapy on transcranial Doppler ultrasonography velocities in children with sickle cell disease. Pediatr Blood Cancer 2011;56 5:777-82. http://www.ncbi.nlm.nih.gov/pubmed/21370410

  • Lal A, Ames BN. Association of chromosome damage detected as micronuclei with hematological diseases and micronutrient status. Mutagenesis 2011;26 1:57-62. http://www.ncbi.nlm.nih.gov/pubmed/21164183

  • Lal A, Goldrich ML, Haines DA, Azimi M, Singer ST, Vichinsky EP. Heterogeneity of hemoglobin H disease in childhood. N Engl J Med 2011;364 8:710-8. http://www.ncbi.nlm.nih.gov/pubmed/21345100

  • Lal A, Porter J, Sweeters N, Ng V, Evans P, Neumayr L, Kurio G, Harmatz P, Vichinsky E. Combined chelation therapy with deferasirox and deferoxamine in thalassemia. Blood Cells Mol Dis 2013;50 2:99-104. http://www.ncbi.nlm.nih.gov/pubmed/23151373

  • Machado RF, Barst RJ, Yovetich NA, Hassell KL, Kato GJ, Gordeuk VR, Gibbs JS, Little JA, Schraufnagel DE, Krishnamurti L, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Onyekwere O, Castro OL, Sachdev V, Waclawiw MA, Woolson R, Goldsmith JC, Gladwin MT, Investigators WP. Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity. Blood 2011;118 4:855-64. http://www.ncbi.nlm.nih.gov/pubmed/21527519

  • Macklin RS, Insel P, Truran D, Vichinsky E, Neumayr L, Armstrong FD, Gold JI, Kesler K, Brewer J, Weiner MW. Neuroimaging Abnormalities in Neurologically Intact Adults with Sickle Cell Anemia: Associations with Cognitive Functioning 2013 (submitted).

  • Maggio A, Filosa A, Vitrano A, Aloj G, Kattamis A, Ceci A, Fucharoen S, Cianciulli P, Grady RW, Prossomariti L, Porter JB, Iacono A, Cappellini MD, Bonifazi F, Cassara F, Harmatz P, Wood J, Gluud C. Iron chelation therapy in thalassemia major: a systematic review with meta-analyses of 1520 patients included on randomized clinical trials. Blood Cells Mol Dis 2011;47 3:166-75. http://www.ncbi.nlm.nih.gov/pubmed/21843958

  • Mansour KM, Kuypers FA, Wang TN, Miller AM, Larkin SK, Morris CR. Secretory phospholipase A2: a marker of infection in febrile children presenting to a pediatric ED. Am J Emerg Med 2011;29 9:1163-8. http://www.ncbi.nlm.nih.gov/pubmed/20708879

  • Marsh AM, Lo L, Cohen RA, Feusner JH. Sorafenib and bevacizumab for recurrent metastatic hepatoblastoma: stable radiographic disease with decreased AFP. Pediatr Blood Cancer 2012;59 5:939-40. http://www.ncbi.nlm.nih.gov/pubmed/22492703

  • Mattsson N, Olsson M, Gustavsson MK, Kosicek M, Malnar M, Mansson JE, Blomqvist M, Gobom J, Andreasson U, Brinkmalm G, Vite C, Hecimovic S, Hastings C, Blennow K, Zetterberg H, Portelius E. Amyloid-beta metabolism in Niemann-Pick C disease models and patients. Metab Brain Dis 2012;27 4:573-85. http://www.ncbi.nlm.nih.gov/pubmed/22935999

  • Mietus-Snyder ML, Shigenaga MK, Suh JH, Shenvi SV, Lal A, McHugh T, Olson D, Lilienstein J, Krauss RM, Gildengoren G, McCann JC, Ames BN. A nutrient-dense, high-fiber, fruit-based supplement bar increases HDL cholesterol, particularly large HDL, lowers homocysteine, and raises glutathione in a 2-wk trial. FASEB J 2012;26 8:3515-27. http://www.ncbi.nlm.nih.gov/pubmed/22549511

  • Morris CR. Arginine and Asthma. In: Nestlé Nutrition Institute Workshop Series. Basel, Switzerland: Karger AG; 2013 (in press).

  • Morris CR, Kim HY, Trachtenberg F, Wood J, Quinn CT, Sweeters N, Kwiatkowski JL, Thompson AA, Giardina PJ, Boudreaux J, Olivieri NF, Porter JB, Neufeld EJ, Vichinsky EP, Thalassemia Clinical Research N. Risk factors and mortality associated with an elevated tricuspid regurgitant jet velocity measured by Doppler-echocardiography in thalassemia: a Thalassemia Clinical Research Network report. Blood 2011;118 14:3794-802. http://www.ncbi.nlm.nih.gov/pubmed/21772051

  • Morris CR, Kim HY, Trachtenberg F, Wood J, Quinn CT, Sweeters N, Kwiatkowski JL, Thompson AA, Giardina PJ, Boudreaux J, Olivieri NF, Porter JB, Neufeld EJ, Vichinsky EP, Thalassemia_Clinical_Research_Network. Risk factors and mortality associated with an elevated tricuspid regurgitant jet velocity measured by Doppler-echocardiography in thalassemia: a Thalassemia Clinical Research Network report. Blood 2011;118 14:3794-802. http://www.ncbi.nlm.nih.gov/pubmed/21772051

  • Morris CR, Kim HY, Wood J, Porter JB, Klings ES, Trachtenberg FL, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Singer ST, Taher A, Neufeld EJ, Thompson AA, Sachdev V, Larkin S, Suh JJ, Kuypers FA, Vichinsky EP. Sildenafil therapy in thalassemia patients with doppler-defined risk for pulmonary hypertension. Haematologica 2013 (in press).

  • Morris CR, Kuypers FA, Lavrisha L, Sweeters N, Stewart M, Ansari M, Gildengorin G, Neumayr L, Vichinsky E. A Randomized, Placebo-Control Trial of Arginine Therapy for the Treatment of Children with Sickle Cell Disease Hospitalized with Vaso-occlusive Pain Episodes. Haematologica 2013 (in press).

  • Musallam KM, Rivella S, Vichinsky E, Rachmilewitz EA. Non-Transfusion-Dependent Thalassemias. Haematologica 2013 (accepted).

  • Musselman JR, Georgieff MK, Ross JA, Tomlinson GE, Feusner J, Krailo M, Spector LG. Maternal pregnancy events and exposures and risk of hepatoblastoma: A Children's Oncology Group (COG) study. Cancer Epidemiol 2013. http://www.ncbi.nlm.nih.gov/pubmed/23312454

  • Nazarov I, Lee JW, Soupene E, Etemad S, Knapik D, Green W, Bashkirova E, Fang X, Matthay MA, Kuypers FA, Serikov VB. Multipotent stromal stem cells from human placenta demonstrate high therapeutic potential. Stem Cells Transl Med 2012;1 5:359-72. http://www.ncbi.nlm.nih.gov/pubmed/23197815

  • Newaskar M, Hardy KA, Morris CR. Asthma in sickle cell disease. ScientificWorldJournal 2011;11:1138-52. http://www.ncbi.nlm.nih.gov/pubmed/21623460

  • Nouraie M, Barst R, Kato GJ, Gibbs JS, Sachdev V, Machado RF, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Taylor JGt, Goldsmith JC, Gladwin MT, Gordeuk V, Walk_Phasst_Investigators. NT-pro BNP is a biomarker of both right and left cardiac function in patients with sickle cell disease: Insights from Walk-PHaSST. Blood 2013 (under review).

  • Nouraie M, Lee JS, Zhang Y, Kanias T, Zhao X, Xiong Z, Oriss TB, Zeng Q, Kato GJ, Gibbs JS, Hildesheim ME, Sachdev V, Barst RJ, Machado RF, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli E, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Goldsmith JC, Gordeuk VR, Gladwin MT, Investigators WP. The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe. Haematologica 2013;98 3:464-72. http://www.ncbi.nlm.nih.gov/pubmed/22983573

  • Oliveros O, Trachtenberg F, Haines D, Gerstenberger E, Martin M, Carson S, Green S, Calamaras D, Hess P, Yamashita R, Vichinsky E. Pain over time and its effects on life in thalassemia. 2013 (in process).

  • Olivieri NF, Pakbaz Z, Vichinsky E. Hb E/beta-thalassaemia: a common & clinically diverse disorder. Indian J Med Res 2011;134:522-31. http://www.ncbi.nlm.nih.gov/pubmed/22089616

  • Olivieri NF, Saunthararajah Y, Thayalasuthan V, Kwiatkowski J, Ware RE, Kuypers FA, Kim HY, Trachtenberg FL, Vichinsky EP, Thalassemia Clinical Research N. A pilot study of subcutaneous decitabine in beta-thalassemia intermedia. Blood 2011;118 10:2708-11. http://www.ncbi.nlm.nih.gov/pubmed/21700776

  • Orgel E, Zung L, Ji L, Finklestein J, Feusner J, Freyer DR. Early Cardiac Outcomes Following Contemporary Treatment for Childhood Acute Myeloid Leukemia: A North American Perspective. Pediatr Blood Cancer 2013. http://www.ncbi.nlm.nih.gov/pubmed/23441080

  • Paulukonis S, Neumayr L, Vichinsky E, RUSH_Project. RuSH SCD Methodology Paper. 2013 (in process).

  • Perilongo G, Malogolowkin M, Feusner J. Hepatoblastoma clinical research: Lessons learned and future challenges. Pediatric Blood & Cancer 2012;59 5:818-21. http://dx.doi.org/10.1002/pbc.24217

  • Porter J, Wood J, Olivieri N, Vichinsky E, Taher A, Neufeld E, Giardina P, Thompson A, Moore B, Evans P, Kim HY, Macklin E, Trachtenberg F. Treatment of heart failure in adults with thelassaemia major: response in patients randomised to deferoxamine with or without deferiprone. 2013 (submitted).

  • Pratini NR, Sweeters N, Vichinsky E, Neufeld JA. Treatment of Classic Pantothenate Kinase-Associated Neurodegeneration with Deferiprone and Intrathecal Baclofen. Am J Phys Med Rehabil 2013. http://www.ncbi.nlm.nih.gov/pubmed/23370589

  • Puumala SE, Ross JA, Feusner JH, Tomlinson GE, Malogolowkin MH, Krailo MD, Spector LG. Parental infertility, infertility treatment and hepatoblastoma: a report from the Children's Oncology Group. Hum Reprod 2012;27 6:1649-56. http://www.ncbi.nlm.nih.gov/pubmed/22473396

  • Quinn CT, Johnson VL, Kim HY, Trachtenberg F, Vogiatzi MG, Kwiatkowski JL, Neufeld EJ, Fung E, Oliveri N, Kirby M, Giardina PJ, Thalassemia Clinical Research N. Renal dysfunction in patients with thalassaemia. Br J Haematol 2011;153 1:111-7. http://www.ncbi.nlm.nih.gov/pubmed/21332704

  • Quinn CT, Stuart MJ, Kesler K, Ataga KI, Wang WC, Styles L, Smith-Whitley K, Wun T, Raj A, Hsu LL, Krishnan S, Kuypers FA, Setty Y, Rhee S, Key NS, Buchanan GR, Centers IotCSC. Tapered oral dexamethasone for the acute chest syndrome of sickle cell disease. Br J Haematol 2011;155 2:263-7. http://www.ncbi.nlm.nih.gov/pubmed/21848879

  • Rapkin L, Feusner J. High-dose acetaminophen with N-acetylcysteine resuce enhances the efficacy of cisplatin chemotherapy. 2013 (submitted).

  • Rienhoff HY, Jr., Viprakasit V, Tay L, Harmatz P, Vichinsky E, Chirnomas D, Kwiatkowski JL, Tapper A, Kramer W, Porter JB, Neufeld EJ. A phase 1 dose-escalation study: safety, tolerability, and pharmacokinetics of FBS0701, a novel oral iron chelator for the treatment of transfusional iron overload. Haematologica 2011;96 4:521-5. http://www.ncbi.nlm.nih.gov/pubmed/21173101

  • Romero Z, Urbinati F, Geiger S, Cooper A, Wherley J, Kaufman M, Hollis R, Senadheera S, Ruiz de Assin R, Sahagian A, Gellis A, Wang X, Gjertson D, DeOliveira S, Kempert P, Shupie S, Abdel-Azim H, Walters MC, Meiselman H, Wenby R, Gruber T, Marder V, Coates T, Kohn D. Transduction of Human Bone Marrow CD34+ Cells by a Lentiviral Vector Carrying a Modified Human ?-Globin Gene for Sickle Cell Disease. 2013 (submitted).

  • Ruggeri A, Eapen M, Scaravadou A, Cairo MS, Bhatia M, Kurtzberg J, Wingard JR, Fasth A, Lo Nigro L, Ayas M, Purtill D, Boudjedir K, Chaves W, Walters MC, Wagner J, Gluckman E, Rocha V, Eurocord R, Center for International B, Marrow Transplant R, New York Blood C. Umbilical cord blood transplantation for children with thalassemia and sickle cell disease. Biol Blood Marrow Transplant 2011;17 9:1375-82. http://www.ncbi.nlm.nih.gov/pubmed/21277376

  • Sabloff M, Chandy M, Wang Z, Logan BR, Ghavamzadeh A, Li CK, Irfan SM, Bredeson CN, Cowan MJ, Gale RP, Hale GA, Horan J, Hongeng S, Eapen M, Walters MC. HLA-matched sibling bone marrow transplantation for beta-thalassemia major. Blood 2011;117 5:1745-50. http://www.ncbi.nlm.nih.gov/pubmed/21119108

  • Sachdev V, Kato GJ, Gibbs JS, Barst RJ, Machado RF, Nouraie M, Hassell KL, Little JA, Schraufnagel DE, Krishnamurti L, Novelli EM, Girgis RE, Morris CR, Rosenzweig EB, Badesch DB, Lanzkron S, Castro OL, Taylor JGt, Hannoush H, Goldsmith JC, Gladwin MT, Gordeuk VR, Investigators WP. Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom. Circulation 2011;124 13:1452-60. http://www.ncbi.nlm.nih.gov/pubmed/21900080

  • Singer ST, Vichinsky EP, Gildengorin G, van Disseldorp J, Rosen M, Cedars MI. Reproductive capacity in iron overloaded women with thalassemia major. Blood 2011;118 10:2878-81. http://www.ncbi.nlm.nih.gov/pubmed/21757620

  • Singer ST, Vichinsky EP, Sweeters N, Rachmilewitz E. Darbepoetin alfa for the treatment of anaemia in alpha- or beta- thalassaemia intermedia syndromes. Br J Haematol 2011;154 2:281-4. http://www.ncbi.nlm.nih.gov/pubmed/21496003

  • Smith S, Witkowski A, Moghul A, Yoshinaga Y, Nefedov M, de Jong P, Feng D, Fong L, Tu Y, Hu Y, Young SG, Pham T, Cheung C, Katzman SM, Brand MD, Quinlan CL, Fens M, Kuypers F, Misquitta S, Griffey SM, Tran S, Gharib A, Knudsen J, Hannibal-Bach HK, Wang G, Larkin S, Thweatt J, Pasta S. Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium. PLoS One 2012;7 10:e47196. http://www.ncbi.nlm.nih.gov/pubmed/23077570

  • Smith WR, Ballas SK, McCarthy WF, Bauserman RL, Swerdlow PS, Steinberg MH, Waclawiw MA, Anemia IotMSoHiSC. The association between hydroxyurea treatment and pain intensity, analgesic use, and utilization in ambulatory sickle cell anemia patients. Pain Med 2011;12 5:697-705. http://www.ncbi.nlm.nih.gov/pubmed/21481164

  • Sobota A, Yamashita R, Xu Y, Trachtenberg F, Kohlbry P, Kleinert DA, Giardina PJ, Kwiatkowski JL, Foote D, Thayalasuthan V, Porter JB, Thompson AA, Schilling L, Quinn CT, Neufeld EJ, Network TCR. Quality of life in thalassemia: a comparison of SF-36 results from the thalassemia longitudinal cohort to reported literature and the US norms. Am J Hematol 2011;86 1:92-5. http://www.ncbi.nlm.nih.gov/pubmed/21061309

  • Sohn EY, Kato R, Noetzli LJ, Gera A, Coates T, Harmatz P, Keens TG, Wood JC. Exercise performance in thalassemia major: Correlation with cardiac iron burden. Am J Hematol 2013;88 3:193-7. http://www.ncbi.nlm.nih.gov/pubmed/23339082

  • Sohn EY, Noetzli LJ, Gera A, Kato R, Coates TD, Harmatz P, Keens TG, Wood JC. Pulmonary function in thalassaemia major and its correlation with body iron stores. Br J Haematol 2011;155 1:102-5. http://www.ncbi.nlm.nih.gov/pubmed/21810090

  • Soupene E, Kuypers FA. Phosphatidylcholine formation by LPCAT1 is regulated by Ca(2+) and the redox status of the cell. BMC Biochem 2012;13:8. http://www.ncbi.nlm.nih.gov/pubmed/22676268

  • Soupene E, Rothschild J, Kuypers FA, Dean D. Eukaryotic protein recruitment into the Chlamydia inclusion: implications for survival and growth. PLoS One 2012;7 5:e36843. http://www.ncbi.nlm.nih.gov/pubmed/22590624

  • Stewart AK, Shmukler BE, Vandorpe DH, Rivera A, Heneghan JF, Li X, Hsu A, Karpatkin M, O'Neill AF, Bauer DE, Heeney MM, John K, Kuypers FA, Gallagher PG, Lux SE, Brugnara C, Westhoff CM, Alper SL. Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S. Am J Physiol Cell Physiol 2011;301 6:C1325-43. http://www.ncbi.nlm.nih.gov/pubmed/21849667

  • Suh J, Kanathezhath B, Shenvi S, Guo H, Zhou A, Tiwana A, Kuypers F, Ames B, Walters M. Metabolomic profiling implicates GSH dysregulation in early experimental GVHD. PlosOne 2013 (under revision).

  • Switzer WM, Shankar A, Trimble SR, Thompson AA, Giardina PJ, Cohen AR, Coates TD, Vichinsky E, Neufeld EJ, Boudreaux JM, Heneine W. Human T Cell Lymphotropic Virus Type 1 Infection Among U.S. Thalassemia Patients. AIDS Res Hum Retroviruses 2013. http://www.ncbi.nlm.nih.gov/pubmed/23409829

  • Thompson A, Kim H, Singer ST, Vichinsky E, Calamaras D, Beatty J, Braunstein J, Yamashita R, Giardina P, Olivieri N, Parmar N, Trachtenberg F, Neufeld E, Kwiatkowski J, Network. TCR. Pregnancy outcomes in women with thalassemia in North America and the UK. 2013 (submitted).

  • Thompson AA, Cunningham MJ, Singer ST, Neufeld EJ, Vichinsky E, Yamashita R, Giardina P, Kim HY, Trachtenberg F, Kwiatkowski JL, Thalassemia Clinical Research Network I. Red cell alloimmunization in a diverse population of transfused patients with thalassaemia. Br J Haematol 2011;153 1:121-8. http://www.ncbi.nlm.nih.gov/pubmed/21323889

  • Tolar J, Mehta PA, Walters MC. Hematopoietic cell transplantation for nonmalignant disorders. Biol Blood Marrow Transplant 2012;18 1 Suppl:S166-71. http://www.ncbi.nlm.nih.gov/pubmed/22226101

  • Trachtenberg F, Haines D, Oliveros O. Design and Implementation of a Study to Assess Pain in Thalassemia. 2013 (in process).

  • Trachtenberg F, Vichinsky E, Haines D, Pakbaz Z, Mednick L, Sobota A, Kwiatkowski J, Thompson AA, Porter J, Coates T, Giardina PJ, Olivieri N, Yamashita R, Neufeld EJ, Thalassemia Clinical Research N. Iron chelation adherence to deferoxamine and deferasirox in thalassemia. Am J Hematol 2011;86 5:433-6. http://www.ncbi.nlm.nih.gov/pubmed/21523808

  • Treadwell M, Telfair J, Gibson RW, Johnson S, Osunkwo I. Transition from pediatric to adult care in sickle cell disease: establishing evidence-based practice and directions for research. Am J Hematol 2011;86 1:116-20. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21061308

  • Treadwell MJ, Alkon A, Styles L, Boyce WT. Autonomic nervous system reactivity: children with and without sickle cell disease. Nurs Res 2011;60 3:197-207. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21532352

  • Trimble S, Reyes N, Thompson A, Giardina P, Cohen A, Coates T, Vichinsky E, Neufeld E, Boudreaux J, Miller C, Grant A. Viral Seroconversion Monitoring in Chronically Transfused Thalassemia Patients in the United States, 2004-2009. 2013 (in process).

  • Trobaugh-Lotrario AD, Feusner J. Hepatoblastoma in patients with Beckwith-Wiedemann Syndrome. 2013 (in process).

  • Trobaugh-Lotrario AD, Feusner JH. Relapsed hepatoblastoma. Pediatric Blood & Cancer 2012;59 5:813-7. http://dx.doi.org/10.1002/pbc.24218

  • Trobaugh-Lotrario AD, Finegold MJ, Feusner JH. Rhabdoid tumors of the liver: rare, aggressive, and poorly responsive to standard cytotoxic chemotherapy. Pediatr Blood Cancer 2011;57 3:423-8. http://www.ncbi.nlm.nih.gov/pubmed/21744471

  • Trobaugh-Lotrario AD, Hirschmann B, Feusner J, Tomlinson G. Congenital Hepatoblastoma. 2013 (in process).

  • Vichinsky E. Advances in the treatment of alpha-thalassemia. In: Blood Rev. 2012/05/29 ed; 2012:S31-4. http://www.ncbi.nlm.nih.gov/pubmed/22631041

  • Vichinsky E. Emerging 'A' therapies in hemoglobinopathies: agonists, antagonists, antioxidants, and arginine. Hematology Am Soc Hematol Educ Program 2012;2012:271-5. http://www.ncbi.nlm.nih.gov/pubmed/23233591

  • Vichinsky E, Bernaudin F, Forni GL, Gardner R, Hassell K, Heeney MM, Inusa B, Kutlar A, Lane P, Mathias L, Porter J, Tebbi C, Wilson F, Griffel L, Deng W, Giannone V, Coates T. Long-term safety and efficacy of deferasirox (Exjade) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease. Br J Haematol 2011;154 3:387-97. http://www.ncbi.nlm.nih.gov/pubmed/21592110

  • Vichinsky E, Neumayr L, Neuropsych_Study. The Safety and Efficacy of Transfusion Compared with Standard Care for the Treatment of Neurologic Dysfunction in Adults with Sickle Cell Disease. 2013 (in process).

  • Vichinsky E, Neumayr L, Trimble S, Giardina P, Cohen AR, Coates TD, Boudreaux J, Neufeld EJ, Kenney K, Grant AM, Thompson AA. Transfusion Complications in Thalassemia: A Report From the Centers for Disease Control and Prevention (CDC). Transfusion 2013 (accepted provisionally).

  • Vichinsky E, Torres M, Minniti C, Barrette S, Habr D, Zhang Y, Files B, CICL670A2201_study_investigators. Efficacy and Safety of Deferasirox Compared with Deferoxamine in Sickle Cell Disease: 2-Year Results Including Pharmacokinetics and Concomitant Hydroxyurea Evaluation. 2013 (submitted).

  • Vichinsky Eea. Prevalence of medical complications in patients with symptomatic thalassemia syndromes: Baseline findings from the Thalassemia Longitudinal Cohort (TLC) study. 2013 (in process).

  • Vichinsky EP. Clinical Manifestations of a-Thalassemia. Cold Spring Harb Perspect Med 2013;(3) 3; 10.1101/cshperspect.a011742. http://perspectivesmedicine.net/content/early/2013/03/28/cshperspect.a011742.full.pdf+html

  • Vichinsky EP. The prevention and management of alloimmunization in sickle cell disease: the benefit of extended phenotypic matching of red blood cells. Immunohematology 2012;28 1:20-3. http://www.ncbi.nlm.nih.gov/pubmed/22646146

  • Vichinsky EP, Ohene-Frempong K, Thein SL, Lobo CL, Inati A, Thompson AA, Smith-Whitley K, Kwiatkowski JL, Swerdlow PS, Porter JB, Marks PW. Transfusion and chelation practices in sickle cell disease: a regional perspective. Pediatr Hematol Oncol 2011;28 2:124-33. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20673030

  • Vichinsky EP, Ohene-Frempong K, Transfusion C. Approaches to transfusion therapy and iron overload in patients with sickle cell disease: results of an international survey. Pediatr Hematol Oncol 2011;28 1:37-42. http://www.ncbi.nlm.nih.gov/pubmed/20673029

  • Wahl SK, Garcia A, Hagar W, Gildengorin G, Quirolo K, Vichinsky E. Lower alloimmunization rates in pediatric sickle cell patients on chronic erythrocytapheresis compared to chronic simple transfusions. Transfusion 2012;52 12:2671-6. http://www.ncbi.nlm.nih.gov/pubmed/22519830

  • Wahl SK, Gildengorin G, Feusner J. Weekend delay in initiation of chemotherapy for acute lymphoblastic leukemia: does it matter? J Pediatr Hematol Oncol 2012;34 1:e8-e11. http://www.ncbi.nlm.nih.gov/pubmed/22146528

  • Walter PB, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Grady RW, Vichinsky E, Olivieri N, Trachtenberg F, Alberti D, Fung E, Ames B, Higa A, Harmatz P, Network TCR. Increased leucocyte apoptosis in transfused beta-thalassaemia patients. Br J Haematol 2013;160 3:399-403. http://www.ncbi.nlm.nih.gov/pubmed/23216540

  • Wang W, Brugnara C, Snyder C, Wynn L, Rogers Z, Kalinyak K, Brown C, Qureshi A, Bigelow C, Neumayr L, Smith-Whitley K, Chui DH, Delahunty M, Woolson R, Steinberg M, Telen M, Kesler K. The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial. Br J Haematol 2011;152 6:771-6. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21275961

  • Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates TD. Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial. Haematologica 2011;96 7:1055-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21393329

  • Yamashita R, Sobota A, Trachtenberg F, Xu Y, Pakbaz Z, Odame I, Thompson A, Haines D, Kleinert D, Giardina P, Quinn C, Kwiatkowski J, Schilling L, Boudreaux J, Neufeld E. The impact of the child with thalassemia on the family: parental assessments 2013 (in process).

  • Zohdi TI, Kuypers FA, Lee WC. Estimation of red blood cell volume fraction from overall permittivity measurements. International Journal of Engineering Science 2011;48 11:1681-91. http://www.sciencedirect.com/science/article/pii/S0020722510000832

Editorials:

Letters:

Abstracts:

  • Aguilar A, Kumar A, Saba J. The effect of sphingadiene treatment on neuroblastoma cells. Sixth CHORI Research Symposium. Oakland, CA: Mar 30, 2012. Children's Hospital & Research Center Oakland.

  • Aguilar AE, Agrawal AK, Feusner J. Central nervous system relapse in pediatric acute lymphoblastic leukemia: Should we be making the diagnosis sooner? American Society of Clinical Oncology (ASCO) Annual Meeting. Chicago, Illinois; June 3 - 7, 2011. http://meetinglibrary.asco.org/content/82921-102

  • Alter BP, Giri N, Calvo KR, Maric I, Arthur DC, Hickstein DD, Hastings CA, Lee MA, Hsu A, Holland SM. Clinically Silent Carriers in Families with Myelodysplastic Syndrome Due to GATA2 Mutations. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.1264. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/1264

  • Aydinok Y, Galanello R, Viprakasit V, Piga A, Harmatz P, Forni GL, Shah FT, Grace RF, Porter J, Vichinsky E, Wood J, Krishnan S, Zhang P, Abi-Saab W, Rienhoff HY, Neufeld E. The safety, tolerability and efficacy of FBS0701, an iron chelator in clinical development for transfusional iron overload: data from 72 weeks of treatment. 18th Congress of the European Hematology Association. Stockholm, Sweden: June 13-16, 2013. Haematologica.

  • Barredo J, Hastings C, Xiaomin Lea. Inferior outcome with reduced dose cranial radiation (12 Gy) in isolated CNS relapse of ALL treated with intensive systemic chemotherapy: A Children's Oncology Group study. 43rd Congress of the International Society of Paediatric Oncology. Auckland, New Zealand; Oct 26-30, 2011. Pediatr Blood & Cancer 57(5). https://www.cure4kids.org/private/courses_documents/m_435/Final%20Abstract%20Book.pdf

  • Chu J, Guo H, Raphael R, Torkildson J, Vichinsky E, Hastings C. Disseminated juvenile xanthogranuloma culminating in bone marrow failure and death. American Society of Pediatric Hematology Oncology (ASPHO) 24th Annual Meeting. Baltimore, Maryland; April 13-16, 2011. Pediatric Blood & Cancer 56(6); p.930. http://www.connect2conferences.com/aspho4/ws_search/index.php?task=detail&abstract_id=424

  • Chung J, Feusner J. Utility of hematologic testing for cases of suspected non-accidental trauma. ASPHO Annual Meeting. New Orleans, LA; May 9-12, 2012. http://www.connect2conferences.com/aspho4/ws_search/index.php?task=detail&abstract_id=806

  • Chung J, Fung EB, Feusner JH. A Pilot Study to Assess Alterations in Trace Element Status in Pediatric Patients with Malignancies. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.3183. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/3183

  • Chung J, Lal A, Vichinsky E. Increasing iron overload following splenectomy in Beta Thalassemia Major. ASPHO Annual Meeting. New Orleans, LA; May 9-12, 2012. Pediatric Blood & Cancer 58(7); p.1076. http://www.connect2conferences.com/aspho4/ws_search/index.php?task=detail&abstract_id=842

  • Douer D, Zickl L, Schiffer CA, Appelbaum FR, Feusner JH, Shepherd LE, Willman CL, Bloomfield CD, Rowe JM, Wiernik PH, Tallman MS. Late Relapses Following All-Trans Retinoic Acid for Acute Promyelocytic Leukemia Are Uncommon, Respond Well to Salvage Therapy and Occur Independently of Prognostic Factors At Diagnosis: Long-Term Follow-up of North American Intergroup Study I0129. 53rd Annual Meeting of the American Society of Hematology. San Diego, CA; Dec 10-13, 2011. Blood 118(21); #83. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/83

  • Earl J, Sun P, Martin K, Quirolo K, Vichinsky E, Hoppe C. Evaluation of Moyamoya Disease in Sickle Cell Anemia Patients After Encephaloduroarteriosynangiosis. 53rd Annual Meeting of the American Society of Hematology. San Diego, California; Dec 10-13, 2011. Blood 118(21); 1059. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/1059

  • Fens M, larkin SK, Morris CR, Fitch B, Scicinski J, Oronsky B, Kuypers FA. NO or No NO, Increased Reduction of Nitrite to Nitric Oxide by Modified Red Blood Cells. 53rd Annual Meeting of the American Society of Hematology. San Diego, California; Dec 10-13, 2011. Blood 118(21); #2125. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/2125

  • Fens MHAM, Larkin SK, Fitch WL, Scicinski J, Oronsky B, Kuypers FA. Treatment with a Novel Dinitroazetidine, Abdnaz, Improves Nitrite Reductase Activity of Sickle Red Blood Cells. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.3246. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/3246

  • Franck PHF, Postma C, Veuger M, Wijermans P, Kuypers FA. A Family with Hereditary Elliptocytosis: Variable Clinical Severity Caused by Three Mutations in the {alpha}-Spectrin Gene. 53rd Annual Meeting of the American Society of Hematology. San Diego, CA; Dec 10-13, 2011. Blood 118(21); #3167. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;118/21/3167

  • Freyer DR, Zung L, Reichman L, Feusner J, Finklestein J, Ruccione K, Gaynon P. Early decline in left ventricular (LV) function in survivors of acute myeloid leukkemia (AML) treated with an anthracycline-intensive regimen. American Society of Pediatric Hematology Oncology (ASPHO) 24th Annual Meeting. Baltimore, Maryland; April 13-16, 2011. http://www.connect2conferences.com/aspho4/ws_search/index.php?task=detail&abstract_id=470

  • Fung E, et_al. Low Magnitude Mechanical Stimulation Increases Bone Mass in Adult Patients with Thalassemia: A Pilot Study. Sixth CHORI Research Symposium. Oakland, CA: Mar 30, 2012. Children's Hospital & Research Center Oakland.

  • Fung EB, Reget K, Haines D, Sawyer A, Lal A. Exploring Vertebral Height Deficits in Patients with Thalassemia and Sickle Cell Disease. 53rd Annual Meeting of the American Society of Hematology. San Diego, California; Dec 10-13, 2011. 118(21); # 3198. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/3198

  • Fung EB, Reget K, Haines D, Sawyer AJ, Lal A. Examing vertebral abnormalities in patients with hemoglobinopathies. Orthopedic Research Society Annual Meeting. Long Beach, California; Jan 13-16, 2011.

  • Galanello R, Aydinok Y, Piga A, Forni GL, Viprakasit V, Harmatz P, Shah F, Grace R, Vichinsky E, Wood J, Peppe J, Jones A, Rienhoff HY, Neufeld E. A 48 week phase 2 study of the safety, tolerability and efficacy of FBS0701, a novel iron chelator for treatment of transfusional iron overload. 17th Congress of the European Hematology Association. Amsterdam, The Netherlands: June 14-17, 2012. Haematologica 97(s1); #0606. http://www.ehaweb.org/congress-and-events/18th-congress/previous-congresses-2/abstract-book/eha-17-amsterdam-2012/

  • Garcia JR. Clofarabine and Ara-C for MRD-Positive leukemia pre-transplantations. TACL Investigator Meeting. San Diego, California; Dec 9, 2011. USC-CHLA Institute for Pediatric Clinical Research (IPCR) oral presentation.

  • Gariepy C, Haines D. Good Vibrations: A Short Term Pilot Study of Low Magnitude Vibration Therapy in Patients with Thalassemia. American Society of Bone and Mineral Research. San Diego, CA: Sept. 19, 2011. #MO0446. http://www.asbmr.org/Meetings/AnnualMeeting/AbstractDetail.aspx?aid=896980b9-7d49-4aa9-8380-9a1e7e268a43

  • Giardina P, Goldberg S, Parkhurst Cain J, Chirnomas D, Esposito J, Paley C, Vichinsky E. The palatability and tolerability of Deferasirox (EXJADE®) taken with meals, different liquids, or crushed and added to food. American Society of Pediatric Hematology/Oncology 24th Annual Meeting. Baltimore, Maryland; April 13-16, 2011. Pediatric Blood & Cancer 56(6); poster #4924. http://dx.doi.org/10.1002/pbc.23092

  • Goel R, Hassell KL, Machado RF, Barst RJ, Yovetich N, Kato GJ, Gordeuk VR, Little JA, Gibbs JSR, Schraufnagel DE, Girgis RE, Rosenzweig EB, Morris CR, Badesch DB, Lanzkron S, Onyekwere O, Nouraie M, Castro OL, Sachdev V, Waclawiw M, Woolson R, Goldsmith JC, Gladwin MT, Krishnamurti L. Non-Cardiopulmonary Factors Affecting the Six-Minute Walk Distance in Patients with Sickle Cell Disease: Results From the Walk-PHaSST Study. 53rd Annual Meeting of the American Society of Hematology. San Diego, California; Dec 10-13, 2011. Blood 118(21); #1074. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;118/21/1074

  • Gonzalez A, Hagar RW, Hoehner C, Fung E. Liver iron, Vitamin D, and bone mineralization in sickle cell disease. CHORI Summer Student Symposium. Oakland, California. poster presentation.

  • Hagar RW. The burden of sickle cell pain. Sickle Cell Adult Provider Network Annual Symposium. Hollywood, Florida. oral presentation.

  • Hagar RW. Chronic renal disease in adult sickle cell patients. 5th Annual Sickle Cell Disease Research and Educational Symposium and Annual National Sickle Cell Scientific Meeting. Hollywood, Florida: 2011. Am J Hematol 86(10); oral presentation. http://onlinelibrary.wiley.com/doi/10.1002/ajh.v86.10/issuetoc

  • Hagar RW, Kurio G, Hoehner C, Earl J, Neumayr L. Cardiac iron in hypertransfused sickle cell patients. 5th Annual Sickle Cell Disease Research and Educational Symposium and Annual National Sickle Cell Scientific Meeting. Hollywood, Florida, 2011. Am J Hematol 86(10); oral presentation. http://onlinelibrary.wiley.com/doi/10.1002/ajh.v86.10/issuetoc

  • Haines D. Pain in Thalassemia: Pervasive and Severe. 2nd Meeting of the Worldwide Initiative on Social Studies on Hemoglobinopathies. Atlanta, GA: March 16, 2012. poster presentation.

  • Hastings C, Hempel C, Browne R. Clinical Experience with Intravenous Infusions of Hydroxy-Propyl-Beta-Cyclodextrin in Identical Twin Patients with Niemann-Pick Type C Disease under Individual Investigator New Drug Exemptions. 2011 Scientific Conference on Niemann-Pick Type C Disease. Notre Dame, Indiana; June 9-11, 2011. oral presentation. http://www.parseghian.org/documents/AbstractsAll.pdf

  • Hastings C, Torkildson J, Raphael R. Intrathecal hydroxyl-propyl-beta-cyclodextrix reverses hearing loss in identifal twin girls with Niemann-Pick Type C Disease. 12th International Congress of Human Genetics/61st Annual Meeting of The American Society of Human Genetics. Montreal, Canada; Oct 11-15, 2011. Poster #1315T. http://www.ichg2011.org/abstracts/fulltext/f10771.htm

  • Heeney M, Mueller B, Baltz B, Paley C, Esposito J, Sharma S, Vichinsky E. Baseline characteristics of patients with sickle cell disease in an ongoing 5-year, prospective, noninterventional registry trial. 53rd Annual Meeting of the American Society of Hematology. San Diego, CA; Dec 10-13, 2011. Blood 118(21); #1060. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/1060

  • Heeney MM, Mueller BU, Baltz B, Adams-Graves P, Yang E, Paley C, Esposito J, Vichinsky EP. 12-Month Follow-up for Patients with Sickle Cell Disease in an Ongoing 3-Year, Prospective, Non-Interventional Registry Trial. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.1010. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/1010

  • Hoehner C, Hagar RW. A Dedicated Over 50 Sickle Cell Clinic. 6th Annual Sickle Cell Disease Research and Educational Symposium and Annual National Sickle Cell Scientific Meeting. Hollywood, Florida; Feb 29-Mar 2, 2012. Am J Hematol 87(7). http://onlinelibrary.wiley.com/doi/10.1002/ajh.23331/abstract

  • Hoppe C, Kuypers FA, Larkin SK, Hagar R, Vichinsky E, Styles LA. Effect of Short-Term Simvastatin Treatment on Endothelial Adhesion Molecules in Sickle Cell Disease: A Pilot Study. 53rd Annual Meeting of the American Society of Hematology. San Diego, CA; Dec 10-13, 2011. Blood 118(21); #1070. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/1070

  • Kamani NR, Walters M, Carter S, Brochstein JA, Eapen M, Levine JE, Logan B, Panepinto J, Parikh S, Pulsipher M, Schultz KR, Shenoy S. Unrelated Donor Cord Blood Transplantation For Children With Severe Sickle Cell Disease: Results Of A Phase Ii Study From The Blood And Marrow Transplant Clinical Trials Network. BMT Tandem Meetings. San Diego, CA: Feb. 1-5, 2012. American Society for Blood and Marrow Transplantation #327. http://www.abstracts2view.com/bmt/view.php?nu=ASBMT12L_372

  • Kanathezhath B, Shenvi S, Johl A, Manmohan R, Bhandhal MK, Oh D, Zhou A, Kuypers FA, Walters MC, Ames BN, Suh J. Systemic And Hepatic Thiol Redox Dysregulation In Graft Versus Host Disease. BMT Tandem Meetings. San Diego, CA: Feb. 1-5, 2012. American Society for Blood and Marrow Transplantation #421. http://www.abstracts2view.com/bmt/view.php?nu=ASBMT12L_259

  • Kanathezhath B, Stanislaus S, Kaplan J, Larkin S, Kuypers F, Walters M. Augmented Regulatory T Cell Response After Photochemical Treatment Alleviates Acute Graft-Versus Host Disease and Improves Survival The American Society for Blood and Marrow Transplantation, BMT Tandem Meeting. Honolulu, Hawaii. 17(2); S331-S2.

  • Kanathezhath B, Suh J, Shenvi S, Guo H, Walters M, Ames B. Glutathione Redox Metabolomic Dysregulation Precedes TNF-? Elevation and Predicts Severity of Gvhd in Experimental Transplantation. BMT Tandem Meetings. Salt Lake City, Utah: Feb. 13-17, 2013. American Society for Blood and Marrow Transplantation #438. https://bmt.confex.com/tandem/2013/webprogram/Paper2122.html

  • Khurana M, Feusner JH, Lee B. Fever at diagnosis of pediatric acute lymphoblastic leukemia (ALL): Are antibiotics really necessary. American Society of Clinical Oncology Annual Meeting. Chicago, Illinois; June 1-5, 2012. Abstract #9553. http://meetinglibrary.asco.org/content/101090-114

  • Killilea D, Suh J, Mattson N, Zetterberg H, Portelius E, Blennow K, Hung Y, Bush A, Hastings C. Characterization of biomarkers during investigative therapy of hydroxyl-propyl-beta-cyclodextrin in Niemann-Pick Type C Disease. 12th International Congress of Human Genetics/61st Annual Meeting of The American Society of Human Genetics. Montreal, Canada; Oct 11-15, 2011. Poster #1299W. http://www.ichg2011.org/abstracts/fulltext/f10865.htm

  • Klaassen R, Merells-Pulcini M, Barrowman N, Vichinsky E, Sweeters N, Kirby M, Neufeld E, Kwiatkowski J, Wu J, Vickars L, Blanchette V, Forgie M, Yamashita R, Wong-Rieger D, Young N. COP 36902: Health-Related Quality of Life of Oral Versus Subcutaneous Chelation in Beta Thalassemia Major. 53rd Annual Meeting of the American Society of Hematology. San Diego, CA; Dec 10-13, 2011. Blood 118(21).

  • Klaassen R, Vichinsky E, Kirby M, Neufeld E, Kwiatkowski J, Wu J, Vickars L, Barrowman N, Merelles-Pulcini M, Yamashita R, Wong-Rieger D, Young NL, Sweeters N. Validation and reliability of a disease-specific quality-of-life measure (the TranQol) in adults with thalassemia major. International Society for Quality of Life Research18th Annual Conference. Denver, Colorado; Oct 26-29, 2011. http://www.isoqol.org/UserFiles/file/2011_conference_program.pdf

  • Klein O, Walters M, George D, Chu R, Goodrich JT, Roman E, Schubert R, Del Toro G. Moyamoya Syndrome Treated With Encephaloduroarteriosynangiosis Followed By Hematopoietic Cell Transplantation In Patients With Sickle Cell Disease. BMT Tandem Meetings. San Diego, CA: Feb. 1-5, 2012. American Society for Blood and Marrow Transplantation #276. http://www.abstracts2view.com/bmt/view.php?nu=ASBMT12L_344

  • Kleinert D, Goldberg S, Parkhurst J, Chimomas D, Esposito J, Paley C, Vichinsky E, Giardina P. A single-arm, open-label study of the palatability and tolerability of deferasirox (Exjade) taken with meals, different liquids, or crushed and added to food. Association of Pediatric Hematology/Oncology Nurses (APHON) 35th Annual Conference & Exhibit. Anaheim, California; Sept 8-10, 2011.

  • Kutlar A, Inati A, Taher AT, El-Beshlawy A, Reid M, Abboud MR, Smith H, Ataga KI, Buchanan GR, Malik P, Koshy N, Neumayr L, Aiello M, Johnson E, White JM, Ghalie RG. A Phase 2 Clinical Study of HQK-1001 (2,2-dimethylbutyrate, sodium salt), a Fetal Hemoglobin Inducer, in Patients with Sickle Cell Disease. 53rd Annual Meeting of the American Society of Hematology. San Diego, California; Dec 10-13, 2011. Blood 118(21); #1066. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;118/21/1066

  • Kutlar A, Reid M, Taher AT, Inati A, Abboud MR, El-Beshlawy A, Buchanan GR, Smith H, Ataga KI, Koshy N, Neumayr LD, Malik P, Alvarez OA, Ward R, White JM, Johnson E, Ghalie RG. A Randomized, Open-Label, Multicenter, Dose Escalation Study of HQK-1001 (2,2-Dimethylbutyrate, Sodium Salt) in Sickle Cell Disease. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.998. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/998

  • Lal A, Sweeters N, Ng V, Haines D, Neumayr L, Kurio G, Harmatz P, Evans P, Porter JB, Vichinsky E. Combined Chelation Therapy with Deferasirox and Deferoxamine In Transfusion-Dependent Thalassemia. 12th International Conference on Thalassemia. Antalya, Turkey; May 11-14, 2011. Thalassemia International Federation.

  • Lalefar N, Agarwal R, Porteus M, Kharbanda S, Weinberg K. Bortezomib As a Treatment for Autoimmune Cytopenia After Bone Marrow Transplant. BMT Tandem Meetings. Salt Lake City, Utah: Feb. 13-17, 2013. American Society for Blood and Marrow Transplantation #125.

  • Lalefar N, Ozeran J. Iron Overload in Childhood Cancer. ASPHO Annual Meeting. New Orleans, LA; May 9-12, 2012. http://www.connect2conferences.com/aspho4/ws_search/index.php?task=detail&abstract_id=687

  • Latronica C, Kuypers FA, Rosenfeld H, Larkin SK, Doniger S, Vichinsky E, Morris CR. Tricuspid Regurgitant Jet Velocity (TRV), Biomarkers of Hemolysis, and Impact of Oxygen Therapy in Children with Sickle Cell Disease (SCD) and Vaso-Occlusive Pain Episodes (VOE). 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.4752. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/4752

  • Magnani JL, Kuypers FA, Patton JT, Larkin SK, Styles L, DeCastro LM, Telen MJ, Wun T, Thackray H. Pan-Selectin Antagonist GMI-1070 Affects Biomarkers of Adhesion, Activation and the Coagulation Cascade in Sickle Cell Adults At Steady State. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.87. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/87

  • Marsh A, Feusner J, Cham E. Are bone marrow core biopsies necessary for the initial diagnosis of acute leukemia? ASPHO Annual Meeting; May 9-12, 2012. New Orleans, LA. http://www.connect2conferences.com/aspho4/ws_search/index.php?task=detail&abstract_id=783

  • Marsh A, Lo L, Feusner J. Sorafenib (Soraf) and bevacizumab (Beva) for recurrent metastatic hepatoblastoma (HB). American Society of Clinical Oncology (ASCO) Annual Meeting. Chicago, Illinois; June 3-7, 2011. http://meetinglibrary.asco.org/content/77392-102

  • Marsh AM, Quirolo KC, Golden C, Vichinsky E. Renal Medullary Carcinoma in an Adolescent with Homozygous Hemoglobin SS. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.4774. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/4774

  • Mietus-Snyder M, Jung S, Ames BN, Flores B, Lal A. Metabolic abnormalities in obese teens may relate to poor diets. American Heart Association Nutrition, Physical Activity and Metabolism / Cardiovascular Disease Epidemiology and Prevention and Nutrition, Physical Activity, and Metabolism 2011 Scientific Sessions. Atlanta, Georgia; Mar 22-25, 2011.

  • Minor M, Harmatz P, Fuentebella J, Haines D, Lal A, Vichinsky E. Practical management of HCV genotype 1a in B thalassemia major with triple therapy. Viral Hepatitis Congress 2012. Frankfurt, Germany; Sep 7-9 2012. . Journal of Viral Hepatitis 19(s3); 10. <Go to ISI>://WOS:000308584500020

  • Morris CR, Barreda F, Leibovich SA, Rutherford M, Saulys A, Stewart M, Lavrisha L, Vichinsky E, Bell M, Treadwell MJ. Quality Improvement Goals for Sickle Cell Disease Pain Management in an Urban Pediatric Emergency Department: We Can Do Better! 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.2101. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/2101

  • Morris CR, Kim H-Y, Trachtenberg F, Wood J, Quinn CT, Sweeters N, Kwiatkowski JL, Thompson AA, Giardina PJ, Boudreaux J, Olivieri NF, Porter JB, Neufeld EJ, Vichinsky EP. Risk Factors And Mortality Associated With Doppler-Defined-Pulmonary Hypertension In Thalassemia Major: A Report From The Thalassemia Clinical Research Network Longitudinal Cohort Study. American Thoracic Society International Conference. Denver, Colorado; May 13-18, 2011. A6441.

  • Morris CR, Kim H-Y, Wood JC, Trachtenberg F, Klings ES, Porter JB, Sweeters N, Olivieri NF, Kwiatkowski JL, Singer ST, Taher AT, Neufeld EJ, Thompson AA, Larkin SK, Suh JH, Vichinsky E, Kuypers FA. Cardiopulmonary and Laboratory Profiling of Patients with Thalassemia At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.2122. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/2122

  • Morris CR, Kim H-Y, Wood JC, Trachtenberg F, Klings ES, Porter JB, Sweeters N, Olivieri NF, Kwiatkowski JL, Singer ST, Taher AT, Neufeld EJ, Thompson AA, Sachdev V, Larkin SK, Suh JH, Kuypers FA, Vichinsky E. Sildenafil Therapy in Patients with Thalassemia and an Elevated Tricuspid Regurgitant Jet Velocity (TRV) On Doppler Echocardiography At Risk for Pulmonary Hypertension: Report From the Thalassemia Clinical Research Network. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.1023. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/1023

  • Morris CR, Kuypers F, Hagar RW, Ansari M, Larkin A, Lavrisha L, Wardlaw M, Zheu A, Vichinsky E, Suh J. Oral glutamine supplementation improves global arginine bioavailability in patients with sickle cell disease and Doppler-defined pulmonary hypertension: Preliminary pharmacokinetic results. 5th Annual Sickle Cell Disease Research and Educational Symposium & Annual National Sickle Cell Disease Scientific Meeting - Symposium and Scientific Meeting. Hollywood, Florida; Feb 23-25, 2011. Am J Hematol 86(10).

  • Morris CR, Kuypers FA, Hagar RW, Ansari M, Larkin S, Lavrisha L, Zhou A, Vichinsky E, Suh J. Metabolic Fate Of Oral Glutamine Supplementation Within Plasma And Erythrocytes Of Patients With Sickle Cell Disease And Pulmonary Hypertension: Preliminary Pharmacokinetics Results. American Thoracic Society International Conference. Denver, Colorado; May 13-18, 2011. A5917.

  • Neufeld EJ, Galanello R, Viprakasit V, Aydinok Y, Piga A, Harmatz P, Forni GL, Shah FT, Grace RF, Porter JB, Vichinsky E, Wood JC, Peppe J, Jones A, Rienhoff HY. Safety, Tolerability and Dose Response of FBS0701, a Novel Iron Chelator for Treatment of Transfusional Iron Overload: Results of a 24-Week Multicenter, International Phase 2 Study. 53rd Annual Meeting of the American Society of Hematology. San Diego, California; Dec 10-13, 2011. Blood 118(21); #690. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/690

  • Porter JB, Walter PB, Neumayr LD, Evans P, Weyhmiller MG, Harmatz P, Wood JC, Miller JL, Weiss G, Yuan Q, Wang ZJ, Grosse R, Schoennagel BP, Meerpohl J, Fischer R, Vichinsky E. Iron Trafficking and Distribution in Transfusional Overload: Insights From Comparing Diamond Blackfan Anemia with Sickle Cell Disease and Thalassemia. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.995. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/995

  • Powell B, Moser B, Stock W, Gallagher G, Wilman C, Stone R, Rowe J, Coutre S, Feusner J, Gregory J, Couban S, Applebaum F, Tallman M, Larson R. Adding Mercaptopurine and Methotrexate to Alternate Week ATRA Maintenance Therapy Does Not Improve the Outcome for Adults with Acute Promyelocytic Leukemia (APL) in First Remission: Results From North American Leukemia Intergroup Trial C9710. 53rd Annual Meeting of the American Society of Hematology. San Diego, CA; Dec 10-13, 2011. Blood 118(21); #258. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/258

  • Radhakrishnan K, Talano J, Keever-Taylor C, Bhatia M, Shenoy S, Walters M, Parsons S, Morris E, Baxter-Lowe LA, Cairo MS. Familial Haploidentical (FHI) T-Cell Depleted (TCD) Transplantation In High-Risk Sickle Cell Disease (IND 14359). BMT Tandem Meetings. San Diego, CA: Feb. 1-5, 2012. American Society for Blood and Marrow Transplantation #265. http://www.abstracts2view.com/bmt/view.php?nu=ASBMT12L_203

  • Singer ST, Vichinsky E, Cedars M, Gildengorin G, Suh J. Oxidative Stress and Reproductive Capacity in Iron Overload Thalassemia Major Women. 53rd Annual Meeting of the American Society of Hematology. San Diego, California; Dec 10-13, 2011. Blood 118(21); #2155. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/2155

  • Styles L, Jakubowski JA, Heiselman DE, Heath LE, Zhou C, Quinn CT, Heeney MM, Redding-Lallinger R, Small DS, Moser BA, Winters KJ. Prasugrel in Children with Sickle Cell Disease: Pharmacokinetic and Pharmacodynamic Characteristics from an Open-Label, Adaptive-Design, Dose-Ranging Study. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.3213. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/3213

  • Suh JH, Kanathezhath B, Swapna S, Guo H, Walters MC, Ames BN. Host Nrf2 -glutathione Redox Dysregulation Precedes TNF-{alpha} Elevation and Predicts Severity of Graft Versus Host Disease in Experimental Transplantation. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.4107. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/4107

  • Thompson A, Kim H, Calamaras D, Beatty J, Singer ST, Vichinsky E, Braunstein J, Yamashita R, Giardina P, Olivieri N, Parmar N, Trachtenberg F, Neufeld E, Kwiatkowski J. Pregnancy outcomes in women with thalassemia in North America and the UK. 12th International Conference on Thalassemia. Antalya, Turkey; May 11-14, 2011. Thalassemia International Federation.

  • Treadwell M, Barreda F, Major K, Walker V, Payton W, Kaur K, Vichinsky E. Mental Health Symptoms, Quality of Life and Barriers to Accessing Health Care in Sickle Cell Disease. 53rd Annual Meeting of the American Society of Hematology. San Diego, CA; Dec 10-13, 2011. Blood 118(21); #337. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/337

  • Vichinsky E. Fetal hemoglobin and its relationship to CNS disease in hemoglobinopathies. 18th Annual Hemoglobin Switching Conference. Monterey, California; June 7-11, 2012.

  • Vichinsky E, Beshlawy AE, Alzoebie A, Bernaudin F, Koussa S, Chotsampancharoen T, El-Ali A, Arrowsmith C, Martin M, El-Alfy M. Long-term safety and effectiveness of deferasirox (Exjade®) in pediatric patients aged 2–<6 years at enrollment: Interim report from a 5-year observational study. 3rd Pan-European Conference on Haemoglobinopathies and Rare Anaemias. Limassol, Cyprus: Oct 24-26, 2012.

  • Vichinsky E, El-Beshlawy A, Alzoebie A, Bernaudin F, Koussa S, Chotsampancharoen T, El-Ali A, Arrowsmith C, Martin N, El-Alfy M. Interim Safety and Effectiveness Results From a 5-Year Observational Study of Deferasirox in Pediatric Patients Aged 2-<6 Years At Enrollment. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.2125. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/2125

  • Vichinsky E, Neumayr L, Trimble S, Thompson AA, Giardina P, Cohen AR, Coates TD, Neufeld EJ, Grant AM, Boudreaux J. Transfusion Complications in Thalassemia: A Report From the Centers for Disease Control and Prevention (CDC). 53rd Annual Meeting of the American Society of Hematology. San Diego, California; Dec 10-13, 2011. Blood 118(21); #340. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;118/21/340

  • Vichinsky E, Torres M, Glass J, Minniti C, Barrette S, Habr D, Lynch N, Yiyun Z, Files B. A Randomized Phase II Study Evaluating the Efficacy and Safety of Deferasirox Versus Deferoxamine in Patients with Sickle Cell Disease (SCD): 2-Year Results Including Pharmacokinetics (PK) and Safety of Deferasirox with Concomitant Hydroxyurea Therapy 53rd Annual Meeting of the American Society of Hematology. San Diego, California; Dec 10-13, 2011. Blood 118(21); #1082. http://abstracts.hematologylibrary.org/cgi/content/abstract/118/21/1082

  • Walter PB, Harmatz P, Higa A, Ng V, Weyhmiller MG, Evans P, Porter JB, Sweeters N, Price J, Manji A, Killilea D, Lal A, Vichinsky E. Innate Immune Cell Expression of Pattern Recognition Receptors From {beta}-Thalassemia Patients During Intensive Combination Chelation Therapy. 54th Annual Meeting of the American Society of Hematology. Atlanta, GA; Dec 8-11, 2012. Blood 120(21); p.1025. http://abstracts.hematologylibrary.org/cgi/content/abstract/ashmtg;120/21/1025

updated 10 Apr 2013

Children's Hospital & Research Center Oakland • 747 52nd Street, Oakland, California 94609 • Phone: (510) 428-3000