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Hematology/Oncology Department
Research Studies Open for Enrollment
Date: 10/22/2018
Title ID/Protocol NCT/Phase Sponsor P.I. Contact
STEM CELL TRANSPLANTATION AND CELLULAR THERAPY
Oncology
Role of KIR-favorably Mismatched Haploidentical Transplantation and KIR-polymorphisms in Determining Outcomes of Children with ALL/AML/MDS Undergoing Allogeneic Hematopoietic Cell TransplantationONC1401 NCT02646839
Phase 1/2
Pediatric Blood and Marrow Transplatn ConsortiumNahal Rose Lalefar, MDMarci Moriarty, RN (510-428-3385 x5396)
Oncology: Early Phase, Leukemia
Pediatric and Young Adult Leukemia Adoptive Therapy. A Phase 1/2 Feasibility and Safety Study of CD19-CAR T Cell Immunotherapy for CD19+ LeukemiaPLAT-02 NCT02028455
Phase 1/2
Seattle Children's HospitalAnu Agrawal, MDMarci Moriarty, RN (510-428-3385 x5396)
Sickle Cell
Bone Marrow Transplantation Compared to Standard Care in Adolescents and Young Adults with Severe Sickle Cell DiseaseBMT-CTN-1503-STRIDE2 NCT02766465
Phase 2
BMT-CTN, Medical College of WisconsinMark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
Phase 1 Study Evaluating Gene Therapy by Transplantation of Autologous CD34 Stem Cells Transduced Ex Vivo with the LentiGlobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell DiseaseHGB-206 02140554
Phase 1
bluebird bio, Inc.Mark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
Reduced Intensity Conditioning for Haploidentical Bone Marrow Transplantation in Patients with Symptomatic Sickle Cell DiseaseBMT-CTN-1507 NCT03263559
Phase 2
BMT-CTN, Medical College of WisconsinMark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
Sickle Cell, Thalassemia
Allogeneic Stem Cell Transplantation of CordIn (Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells) in Patients with HemoglobinopathiesCordIn NCT02504619
Phase 1/2
Gamida Cell LtdMark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
Long Term Follow Up for Patients who have received Allogeneic Stem Cell Transplantation of NiCord/CordIn, Umbilical Cord Blood-derived Ex Vivo Expanded Stem and Progenitor CellsNiCord N/A
Gamida Cell LtdMark Walters, MDJulie Decaris (510-428-3385 x2739)
Sickle Cell, Thalassemia, Hematology
Sample Collection of Bone Marrow, Blood, Peripheral Blood Stem Cells or Umbilical Cord Blood from Patients with Genetic Diseases Affecting the Blood CellsBMT-repository N/A
California Institute for Regenerative MedicineMark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
Thalassemia
Evaluating Efficacy and Safety of Gene Therapy in Transfusion-dependent Beta-Thalassemia Beta0/Beta0 Genotype by Autologous Transplantation of CD34+ Stem Cells Transduced Ex Vivo with Lentiviral BA-T87Q Globin VectorHgb-212 NCT02906202
Phase 3
Bluebird BioAshutosh Lal, MDMarci Moriarty, RN (510-428-3385 x5396)
Open-label, Single-arm Study to Assess Safety, Tolerability, and Efficacy of ST-400 Autologous Hematopoietic Stem Cell Transplant for Treatment of Transfusion-dependent Beta thalassemia (TDT)ST-400-01 NCT03432364
Phase 1/2
Sangamo Therapeutics, Inc.Mark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)

UCSF Benioff Children's Hospital Oakland • 747 52nd Street, Oakland, California 94609 • Phone: (510) 428-3000