Hematology/Oncology Open Research Studies: Neuro-Oncology

	UCSF Benioff Children's Hospital Oakland Hematology/Oncology Department Research Studies Open for Enrollment	Date: 01/26/2021

Neuro-Oncology:

Title	ID/Protocol	NCT/Phase	Sponsor	P.I.	Contact
NCI-COG PEDIATRIC MATCH (MOLECULAR ANALYSIS FOR THERAPY CHOICE) - PHASE 2 SUBPROTOCOL OF AG-120 (IVOSIDENIB) IN PATIENTS WITH TUMORS HARBORING IDH1 MUTATIONS	APEC1621K	NCT04195555 Phase 2	COG	Carla Golden, MD	Sheila Contapay-Tabilin, BSN, RN (510-428-3885 x 2611)<
A Phase 2 Study of Veliparib (ABT-888, IND # 139199) and Local Irradiation, Followed by Maintenance Veliparib and Temozolomide, in Patients with Newly Diagnosed High-Grade Glioma (HGG) without H3 K27M or BRAFV600 Mutations	ACNS1721	NCT03581292 Phase 2	COG	Carla Golden, MD	Sheila Contapay-Tabilin, BSN, RN (510-428-3885 x 2611)<
Establishing Continuous Cell Lines and xenografts from Pediatric Cancers for Biological and Pre-Clinical Therapeutic Studies	ABTR04B1	NCT00898755	COG	Carla Golden, MD	Sheila Contapay-Tabilin, BSN, RN (510-428-3885 x 2611)<
Project:EveryChild A Registry, Eligibility Screening, Biology and Outcome Study	APEC14B1	NCT02402244 N/A	COG	Carla Golden, MD	Sheila Contapay-Tabilin, BSN, RN (510-428-3885 x 2611)<
Genomic Analysis in Pediatric Malignancies	Genomics	N/A	N/A	Tabitha Cooney, MD	Tabitha Cooney, MD
Prospective multi-institutional study to assess the risk of radiation induced vasculopathy and stroke as well as stroke recurrence in children with cancer who received radiation therapy to the neck and/or brain	RadART-Pro	N/A	LaRoche Family	Joseph Torkildson, MD	Joseph Torkildson, MD
Phase 2 Study of Reduced Therapy for Newly Diagnosed Average-Risk WNT-Driven Medulloblastoma Patients	ACNS1422	NCT02724579 Phase 2	COG	Carla Golden, MD	Sheila Contapay-Tabilin, BSN, RN (510-428-3885 x 2611)<
Clinical/Molecular Risk-Tailored Intensive, Compressed Induction Chemotherapy Followed by Consolidation Randomization To Single-Cycle or 3 Tandem Cycles of Marrow-Ablative Chemo with Hematopoietic Progenitor Cell Rescue	Head-Start-4	NCT02875314 Phase 4	Next Consortium, Nationwide Children's	Caroline Hastings, MD	Effie Bourgin

UCSF Benioff Children's Hospital Oakland • 747 52nd Street, Oakland, California 94609 • Phone: (510) 428-3000