logo UCSF Benioff Children's Hospital Oakland
Hematology/Oncology Department
Research Studies Open for Enrollment
Date: 06/23/2019

Sickle Cell Disease:

Title ID/Protocol NCT/Phase Sponsor P.I. Contact
Bone Marrow Transplantation Compared to Standard Care in Adolescents and Young Adults with Severe Sickle Cell DiseaseBMT-CTN-1503-STRIDE2 NCT02766465
Phase 2
BMT-CTN, Medical College of WisconsinMark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
Phase 1 Study Evaluating Gene Therapy by Transplantation of Autologous CD34 Stem Cells Transduced Ex Vivo with the LentiGlobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell DiseaseHGB-206 02140554
Phase 1
bluebird bio, Inc.Mark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
Reduced Intensity Conditioning for Haploidentical Bone Marrow Transplantation in Patients with Symptomatic Sickle Cell DiseaseBMT-CTN-1507 NCT03263559
Phase 2
BMT-CTN, Medical College of WisconsinMark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
Allogeneic Stem Cell Transplantation of CordIn (Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells) in Patients with HemoglobinopathiesCordIn NCT02504619
Phase 1/2
Gamida Cell LtdMark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
Long Term Follow Up for Patients who have received Allogeneic Stem Cell Transplantation of NiCord/CordIn, Umbilical Cord Blood-derived Ex Vivo Expanded Stem and Progenitor CellsNiCord N/A
Gamida Cell LtdMark Walters, MDJulie Decaris (510-428-3385 x2739)
Sample Collection of Bone Marrow, Blood, Peripheral Blood Stem Cells or Umbilical Cord Blood from Patients with Genetic Diseases Affecting the Blood CellsBMT-repository N/A
California Institute for Regenerative MedicineMark Walters, MDMarci Moriarty, RN (510-428-3385 x5396)
A Phase 2a, Randomised, Double-Blind, Placebo-Controlled Study of IMR-687 in Adult Patients with Sickle Cell Anaemia (Homozygous HbSS or Sickle-Beta-0 Thalassemia)Imara NCT03401112
Phase 2a
ImaraWard Hagar, MDSmith, Kacie
Anti-Sickling AgentsAnti-Sickling N/A
UCSF Benioff Children's Hospital OaklandAnne Marsh, MDKacie Smith (510-428-3885 x2752)
Application of the HemeChip Point of Care Device for Real-time Monitoring of Hemoglobin S Levels in Chronically Transfused Patients with Sickle Cell DiseaseHemeChip N/A
Doris Duke Charitable FoundationCarolyn Hoppe, MDCarolyn Hoppe, MD (510-428-3885 x3193)
Association between Low Bone Mineral Density (BMD) and Avascular Necrosis (AVN) Chart Review StudySCD-BMD-AVN N/A
UCSF Benioff Children's Hospital OaklandLynne Neumayr, MDMariam Hameed (510-428-3885 x4151)
Dissemination and Implementation of Stroke Prevention Looking at the Care Environment (DISPLACE)DISPLACE N/A
UCSF Benioff Children's Hospital OaklandCarolyn Hoppe, MDMariam Hameed (510-428-3885 x4151)
Efficacy and Safety of Rivipansel in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell DiseaseGMI-1070 NCT02187003
Phase 3
PfizerLynne Neumayr, MDKacie Smith (510-428-3885 x2752)
Engaging Parents of Children with Sickle Cell Disease and their Providers in Shared-Decision Making for Hydroxyurea (ENGAGE HU)Engage-Hydroxyurea NCT03442114
Patient-Centered Outcomes Research InstituteLynne Neumayr, MDMariam Hameed (510-428-3885 x4151)
Prospective Study to Evaluate Disease Status in Patients with Sickle Cell Disease: Global Regional Network for Database and Discovery (GRNDaD)GRNDaD N/A
Doris Duke Charitable FoundationCarolyn Hoppe, MDMariam Hameed (510-428-3885 x4151)
Randomized, Double-Blind, Placebo-Controlled Multi-Center Study to Assess the Safety, Tolerability, and Efficacy of Riocigut in Patients with Sickle Cell DiseasesSTERIO NCT02633397
Phase 2b
University of PittsburghWard Hagar, MDMariam Hameed (510-428-3885 x4151)
Sickle Cell Disease Implementation Consortium Registry: Collecting and Tracking Health Information for Patients with Sickle Cell DiseaseSCCCI N/A
National Heart, Lung and Blood InstituteMarsha Treadwell, PhDTeleah Slater (510-428-3691)

UCSF Benioff Children's Hospital Oakland • 747 52nd Street, Oakland, California 94609 • Phone: (510) 428-3000