logo Hematology/Oncology Research Studies: Open for Enrollment Date: 12/12/18

Category: ONCOLOGY

The Effectiveness of Lactobacillus plantarum (LBP, IND# 17339) in Preventing Acute Graft-versus-Host Disease (GvHD) in Children undergoing Alternative Hematopoietic Progenitor Cell Transplantation (HCT)

NCT#/Phase: N/A
Phase 3
IRB#: 2018-042
Description: The proposed study is a randomized, double-blinded, placebo-controlled intervention trial to determine the benefit of probiotic therapy in preventing the development of GI aGvHD in children undergoing initial alternative donor alloHCT. Importantly, correlative studies will be performed to elucidate how probiotic therapy affects the microbiome. Discovering such benefits of probiotic therapy may have significant impact on morbidity, mortality, and cost of care in children and adolescents alternative donor undergoing alloHCT.
Inclusion:
Enrollment Status: Open for enrollment
Sponsor: Children's Oncology Group (COG)
Principal Investigator(s): Carla Golden, MD
Contact(s): Christine Ho (510-428-3885 x 2609)
Diane Olzewski (510-428-3885 x 3246)
Study Link: #

UCSF Benioff Children's Hospital Oakland • 747 52nd Street, Oakland, California 94609 &bull Phone: (510) 428-3000